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Application value of tranexamic acid combined with SRI-HAPAM in elderly patients with femoral neck fracture receiving total hip arthroplasty

Published on Mar. 21, 2024Total Views: 297 times Total Downloads: 233 times Download Mobile

Author: SHAN Lidan 1 ZHU Yueying 1 CHEN Haitang 1 HUANG Yishuang 1 HUANG Lintuo 2

Affiliation: 1. Orthopedic Nursing Unit 392, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China 2. Department of Orthopedics, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China

Keywords: Tranexamic acid Staged rehabilitation intervention Health action process approach Femoral neck fracture in the elderly Replacement of total hip

DOI: 10.12173/j.issn.1008-049X.202401053

Reference: SHAN Lidan, ZHU Yueying, CHEN Haitang, HUANG Yishuang, HUANG Lintuo.Application value of tranexamic acid combined with SRI-HAPAM in elderly patients with femoral neck fracture receiving total hip arthroplasty[J].Zhongguo Yaoshi Zazhi,2024, 27(2):279-2868.DOI: 10.12173/j.issn.1008-049X.202401053.[Article in Chinese]

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Abstract

Objective  To explore the application value of stage rehabilitation intervention under the Health action process approach (HAPA) model (SRI-HAPAM) combined with tranexamic acid (TXA) in elderly patients with femoral neck fracture (FNF) undergoing total hip arthroplasty (THA).

Methods  Elderly FNF patients with unilateral THA in the First Affiliated Hospital of Wenzhou Medical University from December 2022 to June 2023 were enrolled. According to the random number table method, the patients were divided into routine nursing (RN) group and TXA+SRI-HAPAM group. The RN group received conventional treatment after surgery, and the TXA+SRI-HAPAM group received TXA combined with SRI-HAPAM after surgery. The bleeding indexes [hidden blood loss (HBL), explicit blood loss (EBL) and blood transfusion volume (BTV)], and the levels of hemoglobin (Hb), C-reactive protein (CRP) and D-dimer (DD) were compared between the two groups at 24 h after surgery. The hip function [joint deformity (JD), joint function (JF), joint pain (JP), joint motion (JM) and total hip function (THF)], anxiety and depression [self-rating anxiety scale and self-rating depression scale], satisfaction with care, and complications were compared between the two groups at 3 months after surgery.

Results  A total of 100 elderly patients with unilateral THA due to FNF were included in the study, including 54 in the TXA+SRI-HAPAM group and 46 in the RN group. Before operation, there was no significant difference in Hb, CRP, DD, JD, JF, JP, JM, THF and SAS between the two groups (P>0.05). At 24 hours after operation, Hb decreased in the two groups, while CRP and DD increased (P<0.05), and the decrease in Hb and the increase in CRP and DD, as well as HBL, EBL and BTV in the TXA+SRI-HAPAM group, were lower than those in the RN group (P<0.05). At 3 months after operation, JD, JF, JP, JM and THF in both groups increased compared with those before operation, while SAS and SDS decreased compared with those before operation (P<0.05), and the functional scores of JD, JF, JP, JM and THF in the TXA+SRI-HAPAM group were significantly higher than those in the RN group, and the scores of SAS and SDS were lower than those in the RN group (P<0.05). 3  months after surgery, the nursing satisfaction of the TXA+SRI-HAPAM group was significantly higher than that of the RN group, and the total complication rate was lower than that of the RN group (P<0.05).

Conclusion  Compared the Routine nursing, TXA combined with SRI-HAPAM more effectively promotes postoperative recovery in patients with THA.

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References

1.齐远博, 李建涛, 刘道宏, 等. 三种内固定装置应用于Pauwels Ⅲ型股骨颈骨折的有限元分析[J]. 中国组织工程研究, 2024, 28(30): 4763-4769. [Qi YB, Li JT, Liu DH, et al. Finite element analysis of three types of internal fixation devices applied to Pauwels type III femoral neck fracture[J]. China Organization Engineering Research, 2024, 28(30): 4763-4769.] DOI: 10.12307/2024.645.

2.朱亚峰. 双极人工股骨头置换术与全髋关节置换术治疗老年股骨颈骨折的疗效比较[J]. 中国实用医药, 2023, 18(21): 74-76. [Zhu YF. Comparison of therapeutic effects between bipolar artificial femoral head replacement and total hip replacement in the treatment of elderly femoral neck fractures[J]. Chinese Practical Medicine, 2023, 18(21): 74-76.] DOI: 10.14163/j.cnki.11-5547/r.2023.21.017.

3.贾振薇, 贾振珩, 关江峰. 当归补血汤加减联合琥珀酸亚铁对老年股骨颈骨折全髋关节置换术后贫血的防治效果[J]. 临床合理用药, 2023, 16(36): 95-98. [Jia ZW, Jia ZH, Guan JF. The preventive and therapeutic effects of modified Danggui Buxue Tang combined with ferrous succinate on anemia after total hip arthroplasty in elderly patients with femoral neck fractures[J]. Clinical Rational Medication, 2023, 16(36): 95-98.] DOI: 10.15887/j. cnki.13-1389/r.2023.36.027.

4.Jin ZQ, Wang LG, Qin J, et al. Direct anterior approach versus posterolateral approach for total hip arthroplasty in the treatment of femoral neck fractures in elderly patients: a meta-analysis and systematic review[J]. Ann Med, 2023, 55(1): 1378-1392. DOI: 10.1080/07853890.2023.2193424.

5.Patrick Widmer P, Oesch P, Bachmann S. Effect of Prehabilitation in form of exercise and/or education in patients undergoing total hip arthroplasty on postoperative outcomes-a systematic review[J]. Medicina (Kaunas), 2022, 58(6): 742. DOI: 10.3390/medicina58060742.

6.Picard F, Deakin A, Balasubramanian N, et al. Minimally invasive total knee replacement: techniques and results[J]. Eur J Orthop Surg Traumatol, 2018, 28(5): 781-791. DOI: 10.1007/s00590-018-2164-4.

7.唐骞, 陈峰, 翟吉良, 等. 优化出血管理模式对颈椎后路椎管扩大成形术围手术期失血量的影响[J]. 中华骨与关节外科杂志, 2023, 16(11): 1033-1039. [Tang Q, Chen F, Zhai JL, et al. The effect of optimizing bleeding management mode on perioperative blood loss during posterior cervical laminoplasty[J]. Chinese Journal of Orthopedic and Joint Surgery, 2023, 16(11): 1033-1039.] DOI: 10.3969/j. issn.2095-9958.2023.11.10.

8.陶崑, 黄哲宇, 赵立明, 等. 氨甲环酸在股骨颈骨折全髋关节置换围手术期的应用[J]. 中华骨与关节外科杂志, 2023, 16(7): 596-600. [Tao K, Huang ZY, Zhao LM, et al. The application of tranexamic acid in the perioperative period of total hip arthroplasty for femoral neck fractures[J]. Chinese Journal of Orthopedic and Joint Surgery, 2023, 16(7): 596-600.] DOI: 10.3969/j.issn.2095-9958. 2023.07.04.

9.王亚军, 郭建平. 氨甲环酸联合改良鸡尾酒疗法在全髋关节置换术后康复的疗效分析[J]. 北华大学学报(自然科学版), 2023, 24(1): 88-92. [Wang YJ, Guo JP. Analysis of the therapeutic effect of tranexamic acid combined with improved cocktail therapy on postoperative rehabilitation of total hip arthroplasty[J]. Journal of Beihua University (Natural Science Edition), 2023, 24(1): 88-92.] DOI: 10.11713/j.issn.1009-4822.2023.01.016.

10.李博文, 李世清, 周君. 全髋关节置换术应用氨甲环酸后于不同时间启用抗凝药物对凝血功能影响的对比研究[J]. 医药论坛杂志, 2022, 43(14): 26-29.[Li BW, Li SQ, Zhou J. A comparative study on the effects of using anticoagulants at different times after the application of tranexamic acid in total hip replacement surgery on coagulation function[J]. Journal of Medical Forum, 2022, 43(14): 26-29.] http://qikan.cqvip.com/Qikan/Article/Detail?id=7108167546.

11.陈拓, 温科伟, 滕立初, 等. 氨甲环酸对全髋关节置换术患者术后出血、凝血功能及下肢深静脉血栓的影响[J]. 血管与腔内血管外科杂志, 2022, 8(6): 713-717. [Chen T, Wen KW, Teng LC, et al. The effect of tranexamic acid on postoperative bleeding, coagulation function, and deep vein thrombosis in patients undergoing total hip arthroplasty[J]. Journal of Vascular and Endovascular Surgery, 2022, 8(6): 713-717.] DOI: 10.19418/j.cnki.Issn2096-0646.2022.06.15.

12.Wainwright TW, Gill M, McDonald DA, et al. Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations[J]. Acta Orthop, 2020, 91(1): 3-19. DOI: 10.1080/17453674.2019.1683790.

13.Wang W, Tang C, Ji QL, et al. Use of multiple nursing interventions (cluster nursing) in ABO hemolytic disease of neonates and evaluation of its effect[J]. J Int Med Res, 2020, 48(1): 300060519887630. DOI: 10.1177/0300060519887630.

14.Husby VS, Foss OA, Husby OS, et al. Randomized controlled trial of maximal strength training vs. standard rehabilitation following total knee arthroplasty[J]. Eur J Phys Rehabil Med, 2018, 54(3): 371-379. DOI: 10.23736/S1973-9087.17.04712-8.

15.寇晓平, 潘卫宇, 王晓雨, 等. HAPA模型下阶段式康复护理在股骨颈骨折人工髋关节置换术后患者中的应用[J]. 齐鲁护理杂志, 2023, 29(14): 1-3. [Kou XP, Pan WY, Wang XY, et al. The application of phased rehabilitation nursing under the HAPA model in patients after artificial hip replacement surgery for femoral neck fractures[J]. Qilu Journal of Nursing, 2023, 29(14): 1-3.] DOI: 10.3969/j. issn.1006-7256.2023.14.001.

16.潘竹, 秦然, 宋华荣, 等. 侧卧位直接前方入路与Hardinge入路行初次全髋关节置换在老年股骨颈骨折患者中的早期疗效比较[J]. 哈尔滨医科大学学报, 2021, 55(6): 648-653. [Pan Z, Qin R, Song HR, et al. Comparison of early therapeutic effects of initial total hip arthroplasty in elderly patients with femoral neck fractures using the lateral position direct anterior approach and the Hardinge approach[J]. Journal of Harbin Medical University, 2021, 55(6): 648-653.] DOI: 10.3969/j.issn. 1000-1905.2021.06.018.

17.李丽, 张秀秀, 巴蕊. ABC-X模型在改善结肠癌负性情绪和生活质量中的应用效果分析[J]. 实用中医内科杂志, 2022, 36(3): 141-143. [Li L, Zhang XX, Ba R. Analysis of the application effect of ABC-X model in improving negative emotions and quality of life in colon cancer[J]. Journal of Practical Traditional Chinese Medicine Internal Medicine, 2022, 36(3): 141-143.] DOI: 10.13729/j.issn.1671-7813. Z20211421.

18.Rodríguez-Herrera C, López-Jiménez JDJ, Toro-Valero AD, et al. The newcastle satisfaction with nursing scales in a mexican oncology hospital[J]. Afr Health Sci, 2021, 21(1): 60-66. DOI: 10.4314/ahs.v21i1.10.

19.Ye SW, Chen MJ, Luo Y, et al. Comparative study of carbazochrome sodium sulfonate and tranexamic acid in reducing blood loss and inflammatory response following direct anterior total hip arthroplasty: a prospective randomized controlled trial[J]. Int Orthop, 2023, 47(10): 2553-2561. DOI: 10.1007/s00264-023-05853-3.

20.Hochreiter J, Hejkrlik W, Emmanuel K, et al. Blood loss and transfusion rate in short stem hip arthroplasty. A comparative study[J]. Int Orthop, 2017, 41(7): 1347-1353. DOI: 10.1007/s00264-016-3365-2.

21.Li L, Pan H, Liu GQ, et al. Value of tranexamic acid and progressive nursing in accelerating postoperative rehabilitation after total knee arthroplasty[J]. Altern Ther Health Med, 202, 29(1): 111-117. https://pubmed.ncbi.nlm.nih.gov/35951070/.

22.胡笑峰. 老年骨质疏松性骨折的高危因素与预防管理措施[J]. 中医药管理杂志, 2016, 24 (14): 106-107. [Hu XF. High risk factors and preventive management measures for elderly osteoporotic fractures[J]. Journal of Traditional Chinese Medicine Management, 2016, 24 (14): 106-107.] DOI: 10.16690/j.cnki.1007-9203.2016.14.050.

23.吴丰寅, 陈盈盈, 何凡, 等. 系统护理模式对老年髋骨骨折患者术后恢复的影响[J]. 中医药管理杂志, 2017, 25 (23): 123-126. [Wu FY, Chen YY, He F, et al. The impact of systematic nursing mode on postoperative recovery of elderly patients with hip fractures[J]. Journal of Traditional Chinese Medicine Management, 2017, 25(23): 123-126.] DOI: 10.16690/j.cnki.1007-9203.2017.23.052.

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