Analysis of drug treatment of a suspected CKD 5 patient with acute hyperkalemia caused by traditional Chinese medicine

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Author: LIANG Huan ^1, ²  ZHENG Tao ^1, ² XIE Zhao ^2, ³

Affiliation: 1. Department of Pharmacy, Shiyan Taihe Hospital (Affiliated Hospital of Hubei University of Medicine), Shiyan 442000, Hubei Province, China 2. College of Pharmacy, Hubei University of Medicine, Shiyan 442000, Hubei Province, China 3. College of Traditional Chinese Medicine, Shiyan Taihe Hospital (Affiliated Hospital of Hubei University of Medicine), Shiyan 442000, Hubei Province, China

Keywords: Traditional Chinese medicine Hyperkalemia Clinical pharmacist Pharmacy monitoring

DOI: 10.12173/j.issn.1008-049X.202310137

Reference: LIANG Huan, ZHENG Tao, XIE Zhao.Analysis of drug treatment of a suspected CKD 5 patient with acute hyperkalemia caused by traditional Chinese medicine[J].Zhongguo Yaoshi Zazhi,2024, 27(1):177-180.DOI: 10.12173/j.issn.1008-049X.202310137.[Article in Chinese]  Copied

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Abstract

To explore the thinking and working mode of clinical pharmacists of traditional Chinese medicine participating in clinical, the drug treatment was analyzed by an acute hyperkalemia patient suspected of CKD 5 caused by traditional Chinese medicine. This case is a CKD 5 patient. Since proteinuria was found for 8 years, bilateral lower limb edema was intermittent for 4 years, and the recurrence was aggravated for 1 week, the patient was admitted to the hospital. In the Department of Traditional Chinese Medicine, the patient received standard and reasonable antiplatelet, lipid regulation, kidney protection, anemia improvement, blood pressure reduction, and heart load reduction, Traditional Chinese medicine decoction, traditional Chinese patent medicines. The patient's condition improved, but the newly emerging hyperkalemia prolonged the patient's hospital stay. After the treatment of blood potassium lowering drugs, the blood potassium still increased repeatedly. For this reason, clinical Chinese pharmacists assisted clinicians to find out the factors that caused the repeated increase of blood potassium in combination with existing domestic and foreign literature. Finally, considering the high possibility of traditional Chinese medicine, they stopped using traditional Chinese medicine and continued to use blood potassium lowering drugs, and the blood potassium returned to normal. Hyperkalemia caused by traditional Chinese medicine is not common in clinical practice and often is ignored. It can be seen that clinical pharmacists can participate in pharmaceutical care to find adverse drug reactions as soon as possible and ensure the safety of drug use.

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