Effects of Anemarrhenae Rhizoma on the dissolution of 6 inorganic elements in Gypsum Fibrosum under different compatibility ratio based on grey correlation analysis and TOPSIS model

Published on Dec. 28, 2023Total Views: 383 times Total Downloads: 269 times Download Mobile

Author: Xiao-Dong YANG  Guo-Wei LI Wen-Ping WU Xiao-Lin LIU Xiang-Dong CHEN Ju-Lin XING Wei PANG Li-Ye PAN

Affiliation: Guangdong Yi Fang Pharmaceutical Co.,Ltd, Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granule, Foshan 528244, Guangdong Province, China

Keywords: Gypsum Fibrosum Anemarrhenae Rhizoma Inductively coupled plasma mass spectrometry Grey correlation analysis Technique for order preference by similarity to an ideal solution

DOI: 10.12173/j.issn.1008-049X.202209417

Reference: Xiao-Dong YANG, Guo-Wei LI, Wen-Ping WU, Xiao-Lin LIU, Xiang-Dong CHEN, Ju-Lin XING, Wei PANG, Li-Ye PAN.Effects of Anemarrhenae Rhizoma on the dissolution of 6 inorganic elements in Gypsum Fibrosum under different compatibility ratio based on grey correlation analysis and TOPSIS model[J].Zhongguo Yaoshi Zazhi,2023,26(11):346-354.DOI: 10.12173/j.issn.1008-049X.202209417.[Article in Chinese]  Copied

Abstract
Full-text
References

Abstract

Objective To discuss the effect of Anemarrhenae Rhizoma with different proportions on the dissolution of 6 inorganic elements (K, Ti, Sr, Ba, Ca, Mg) in Gypsum Fibrosum under different compatibility based on grey correlation analysis and technique for order preference by similarity to an ideal solution (TOPSIS) method and to provide reference for clinical application.

Methods Inductively coupled plasma mass spectrometry (ICP-MS) was established for simultaneous analysis of inorganic elements K, Ti, Sr, Ba, Ca, Mg in Gypsum Fibrosum - Anemarrhenae Rhizoma. The gray correlation ananlysis and TOPSIS method were used to comprehensively analyze the changes of six inorganic elements in Gypsum Fibrosum under different compatibility.

Results The findings of the ICP-MS determination of inorganic elements in Gypsum Fibrosum - Anemarrhenae Rhizoma were good in terms of linearity, precision, repeatability and stability. The average recovery was 81.78%-104.13%, and the RSD was 2.10%-4.62% (n=6). The dissolution of six inorganic elements in Gypsum Fibrosum after compatibility with different proportions of Anemarrhena Rhizoma was significantly higher than that of Gypsum Fibrosum single decoction (P<0.05). The dissolution scores of six inorganic elements in Gypsum Fibrosum were the highest when the compatibility proportion of Gypsum Fibrosum - Anemarrhenae Rhizoma was 30∶9.

Conclusion ICP-MS is a sensitive and accurate method for determining K, Ti, Sr, Ba, Ca and Mg in Gypsum Fibrosum- Anemarrhenae Rhizoma. The best compatibility ratio of Gypsum Fibrosum - Anemarrhenae Rhizoma is 30∶9, which can effectively improve the dissolution of six inorganic elements in Gypsum Fibrosum, and provide the basis for the further compatibility study of Gypsum Fibrosum and Anemarrhenae Rhizoma.

Full-text

Please download the PDF version to read the full text: download

References

1.中国药典2020年版. 一部[S]. 2020: 98．

2.王薇, 周才新, 张义生, 等. 不同产地石膏中微量元素的比较分析[J]. 中国药师, 2014, 17(6): 972-974. [Wang W, Zhou CX, Zhang YS, et al. Comparative analysis of trace elements in gypsum from different regions[J]. China Pharmacist, 2014, 17(6): 972-974.] DOI: 10.3969/j.issn.1008-049X.2014.06.028.

3.田腾跃, 包永睿, 孟宪生, 等. 基于ICP-MS法不同产地石膏中无机元素分析[J]. 中华中医药学刊, 2017, 35(4): 1041-1043. [Tian TY, Bao YR, Meng XS, et al. Analysis of inorganic elements in gypsum fibrosum from different origins based on ICP-MS[J]. Chinese Acrchives of Traditional Chinese Medicine, 2017, 35(4): 1041-1043.]DOI: 10.13193/j.issn.1673-7717.2017.04.075.

4.王凤秀, 翟华强, 王永炎, 等. 中药煎煮历史源流与技术研究[J]. 山东中医药大学学报, 2018, 42(2): 109-112.[Wang FX, Zhai HQ, Wang YY, et al. Study on decoction history and technology of traditional chinese medicine[J]. Journal of Shandong University of TCM, 2018, 42(2): 109-112.] DOI: 10.16294/j.cnki.1007-659x.2018.02.005.

5.任艳青, 甄亚钦, 李葆林, 等. 淡豆豉与栀子配伍降低栀子肝脏毒性的研究[J]. 中药药理与临床, 2017, 33(4): 94-97. [Ren YQ, Zhen YQ, Li BL, et al. Study on the compatibility of semen sojae and fructus gardeniae to reduce the liver toxicity of fructus gardeniae[J]. Pharmacology and Clinics of Chinese Materia Medica, 2017, 33(4): 94-97.] DOI: 10.13412/j.cnki.zyyl.2017.04.026.

6.孟娴.中药海藻与甘草配伍致毒增毒作用机理研究[D]. 南京: 南京中医药大学, 2018.

7.乔三洋, 王学勇, 李耿, 等. 基于化学全息研究四物汤煎煮溶出规律[J]. 中草药, 2020, 51(19): 4960-4971. [Qiao SY, Wang XY, Li G, et al. Dissolution rule of siwu decoction by different decocting methods based on chemistry holography[J]. Chinese Traditional and Herbal Drugs, 2020, 51(19): 4960-4971.] DOI: 10.7501/j.issn.0253-2670.2020.19.015.

8.郭琴. 基于蛋白自组装探讨芍药—甘草药对配伍的物质基础[D]. 北京: 中国中医科学院, 2022.

9.李媛, 池加美. 丹参-葛根药对中7种成分的含量测定及其配伍影响考察[J]. 中国药师, 2021, 24(12): 2280-2283. [Li Y, Chi JM. Content determination and compatibility of 7 components in drug pair salvia miltiorrhiza and radix puerariae[J]. China Pharmacist, 2021, 24(12): 2280-2283.] DOI: 10.19962/j.cnki.issn 1008-049X.2021.12.030.

10.宋哲, 黄志艳, 冯钰, 等. 基于数据挖掘研究含石菖蒲-远志药对方剂的组方规律[J]. 中国中药杂志, 2022, 47(6): 1687-1693. [Song Z, Huang ZY, Feng Y, et al. Data mining-based analysis of formulation rules for prescriptions containing herbal pair acori tatarinowii rhizoma-polygalae radix[J]. China Journal of Chinese Materia Medica, 2022, 47(6): 1687-1693.] DOI: 10.19540/j.cnki.cjcmm.20211203.502.

11.肖观林, 钟惠娴, 陈伟韬, 等. 白虎汤单煎、合煎化学成分差异研究[J]. 中成药, 2023, 45(4): 1372-1377. [Xiao GL, Zhong HX, Chen WT,et al, Study on the difference of chemical constituents between single decoction and combined decoction of Baihu Decoction[J]. Chinese Traditional Patent Medicine, 2023, 45(4): 1372-1377. DOI: 10.3969/j.issn.1001-1528.2023.04.060.

12.陈杰,刘金涛,马洪武.参母石膏汤联合门冬胰岛素30治疗二甲双胍失效性2型糖尿病的疗效及对血糖水平、胰岛素抵抗的影响[J]. 四川中医, 2017, 35(9): 83-85. [Chen J, Liu JT, Ma HW. Effect of Shenmu Shigao decoction combined with insulin aspart 30 on metformin ineffective type 2 diabetes mellitus and its effect on blood glucose level and insulin resistance[J]. Journal of Sichuan of Traditional Chinese Medicine, 2017, 35(9): 83-85. DOI: CNKI:SUN:SCZY.0.2017-09-033.

13.陈士林, 刘安, 李琦, 等. 中药饮片标准汤剂研究策略[J]. 中国中药杂志, 2016, 41(8): 1367-1375. [Chen SL, Liu A, Li Q, et al. Research strategies in standard decoction of medicinal slices[J]. China Journal of Chinese Materia Medica, 2016, 41(8): 1367-1375.] DOI: 10.4268/cjcmm20160801.

14.范耀耀, 罗宇琴, 李国卫, 等. 基于灰色关联度分析与TOPSIS模型的不同产地射干标准汤剂质量评价[J]. 中药材, 2022, 45(3): 659-663. [Fan YY, Luo YQ, Li GW, et al. Quality evaluation of Belamcandae Rhizoma standard decoction from different producing areas based on grey correlation analysis and TOPSIS model[J]. Journal of Chinese Medicinal Materials, 2022, 45(3): 659-663.] DOI: 10.13863/j.issn1001-4454.2022.03.024.

15.李运,张霁,徐福荣,等. 多指标决策分析TOPSIS对三七的质量评价研究[J]. 中草药, 2017, 48(22): 4764-4771. [Li Y, Zhang J, Xu FR, et al. Multiple attribute decision making analysis TOPSIS on quality evaluation study of Panax notoginseng[J]. Chinese Traditional and Herbal Drugs, 2017, 48(22): 4764-4771.] DOI: 10.7501/j.issn.0253-2670.2017.22.027.

16.吕培, 李祥, 陈建伟, 等. ICP-OES用于麻杏石甘汤中的无机元素分析[J]. 现代中药研究与实践, 2010, 24(6): 66-68. [Lyu P, Li X, Chen JW, et al. Studyon elemental speciation analysis of Maxingshigan decoction by ICP-OES[J]. Research and Practice on Chinese Medicines, 2010, 24(6): 66-68.] DOI: CNKI:SUN:JZZY.0.2010-06- 032.

17.马强, 苏琨, 苏燕, 等. 不同配伍条件下白虎汤中钙离子溶出规律研究[J]. 时珍国医国药, 2010, 21(9): 2178-2179. [Ma Q, Su K, Su Y, et al. Study with contents of calcium ion dissolution on compatible regularity of Baihu decoction[J]. Lishizhen Medicine and Materia Medica Research, 2010, 21(9): 2178-2179.] https://www.cnki.net/.

18.梁艳妮, 余沛, 王征, 等. 麻黄与石膏不同配伍对主要成分溶出量的影响[J]. 中国药师, 2019, 22(1): 48-52. [Liang YN, Yu P, Wang Z, et al. Influence of different compatibility of ephedra and gypsum on the dissolution of main effective constituents[J]. China Pharmacist, 2019, 22(1): 48-52.] DOI: 10.3969/j.issn.1008-049X.2019.01.012.